Blar i forfatter "Lijfering, Willem M."

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    • Effect of lower-leg trauma and knee arthroscopy on procoagulant phospholipid-dependent activity 

      Touw, Carolina E.; Nemeth, Banne; Lijfering, Willem M.; van Adrichem, Raymond A.; Wilsgård, line; Latysheva, Nadezhda; Ramberg, Cathrine; Nelissen, Rob G. H. H.; Hansen, John Bjarne; Cannegieter, Suzanne C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-08)
      Background: Lower-leg injury and knee arthroscopy are both associated with venous thromboembolism (VTE). The mechanism of VTE in both situations is unknown, including the role of procoagulant microparticles. This may provide useful information for individualizing thromboprophylactic treatment in both patient groups.<p> <p>Objective: We aimed to study the effect of (1) lower-leg trauma and (2) ...

    • Prediction of recurrent venous thrombosis in all patients with a first venous thrombotic event: The Leiden Thrombosis Recurrence Risk Prediction model (L-TRRiP) 

      Timp, Jasmijn F.; Brækkan, Sigrid Kufaas; Lijfering, Willem M.; van Hylckama Vlieg, Astrid; Hansen, John-Bjarne; Rosendaal, Frits Richard; le Cessie, Saskia; Cannegieter, Suzanne C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-11)
      <i>Background</i> - Recurrent venous thromboembolism (VTE) is common. Current guidelines suggest that patients with unprovoked VTE should continue anticoagulants unless they have a high bleeding risk, whereas all others can stop. Prediction models may refine this dichotomous distinction, but existing models apply only to patients with unprovoked first thrombosis. We aimed to develop a prediction ...

    • Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study 

      Småbrekke, Birgit; Rinde, Ludvig Balteskard; Mathisen Hald, Erin; Njølstad, Inger; Mathiesen, Ellisiv B.; Johnsen, Stein Harald; Hansen, John-Bjarne; Brækkan, Sigrid Kufaas; Lijfering, Willem M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-05)
      <p><i>Background</i>: Whether a relationship between atherosclerosis and subsequent venous thromboembolism (VTE) exists is controversial.</p> <p><i>Objective</i>: To investigate the association between carotid atherosclerosis and VTE by using repeated measurements of intima media thickness (IMT) and total plaque area (TPA) in participants recruited from the general population.</p> <p><i>Methods</i>: ...

    • Rosuvastatin treatment decreases plasma procoagulant phospholipid activity after a VTE: A randomized controlled trial 

      Ramberg, Cathrine; Hindberg, Kristian; Biedermann, Joseph S.; Cannegieter, Suzanne C.; van der Meer, Felix J.; Snir, Omri; Leebeek, Frank W. G.; Kruip, Marieke J. H. A.; Hansen, John Bjarne; Lijfering, Willem M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-25)
      Background - Venous thromboembolism (VTE) is a frequent cardiovascular disease with severe complications, including recurrence and death. There is a great need for alternative prophylactic treatment options as anticoagulation is accompanied by increased bleeding risk. Statins are reported to reduce the risk of incident and recurrent VTE, but the mechanisms are elusive. Procoagulant phospholipids ...